Joshua Budhu, Neuro-Oncologist at Memorial Sloan Kettering Cancer Center, shared a post on LinkedIn:
“I’m excited to share our new review published in Cancers:
“The Impact of Sociodemographic Disparities on Health-Related Quality of Life for Adults with Gliomas.”
Grateful to collaborate with Michael Perez (Memorial Sloan Kettering Cancer Center Neuro-Oncology Fellow) and Devon Riegel (Weill Cornell Medicine Neurology Resident) on this work.
Gliomas are the most common malignant primary brain tumors and profoundly affect patients’ lives, not only through survival outcomes but also through their effects on physical, cognitive, emotional, and social functioning.
In this paper, we apply the World Health Organization’s health-related quality of life (HRQoL) framework to examine how glioma diagnoses and treatments influence multiple domains of life, including physical capacity, psychological well-being, independence, social relationships, and environmental factors.
Importantly, we also highlight how sociodemographic factors and structural inequities influence these outcomes. Prior studies have demonstrated disparities in access to surgery, radiation, and chemotherapy among patients with gliomas, which likely contributes to differences in both survival and quality of life.
Our review discusses several opportunities to improve patient-centered outcomes, including:
- Integrating routine HRQoL assessments into clinical care and clinical trials
- Expanding supportive and rehabilitative services
- Addressing financial toxicity and structural barriers to care
- Improving representation and diversity in neuro-oncology research
As treatments improve and patients live longer, quality of life must remain a central outcome in neuro-oncology, and addressing disparities is essential to achieving equitable care.”
Title: The Impact of Sociodemographic Disparities on Health-Related Quality of Life for Adults with Gliomas
Authors: Michael A. Perez, Devon C. Riegel and Joshua Amit Budhu.

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