Drew Moghanaki, Professor, Chief of Thoracic Oncology at the Department of Radiation Oncology and Stanley Iezman and Nancy Stark Endowed Chair in Thoracic Radiation Oncology Research at David Geffen School of Medicine at UCLA, and Chief Medical Officer of Respirati, shared a post on X:
“Large Study from VA Examines Smoking Duration as Metric to Expand Eligibility for Lung Cancer Screening
A retrospective cohort study involving 960,770 patients in the Veterans Health Administration found that tobacco smoking duration (TSD) performed as well as tobacco pack years (TPY) in predicting lung cancer risk and expanded screening eligibility with fewer missed diagnoses (Abstract 8004).
The study compared risk-adjusted 5-year lung cancer incidence based on 2013 guidelines (≥ 30 TPY, quit within 15 years), revised 2021 guidelines (≥ 20 TPY, quit within 15 years), the proposed TSD criterion (≥ 20 TSD), and never smoking. More than half of the cohort (59.4%) qualified for the TSD criterion, and 22.3% of those individuals did not meet the 2021 TPY criteria, suggesting that the TSD criterion would increase the eligible screening population by 28.8%. Using TSD also increased screening eligibility among Black individuals (54.0% to 83.7%) and women (55.1% to 83.7%).”
Title: Redefining lung cancer screening eligibility: Smoking duration vs. pack-years in a national VA cohort of nearly 1 million patients.
Authors: Brendan Heiden, Daniel B. Eaton Jr., Varun Puri, Whitney S. Brandt, Theodore S. Thomas, Martin W. Schoen, Haley Tupper, Matthew P. Smeltzer, Drew Moghanaki, Lawrence Benjamin
Read the Full Abstract.
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