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Clifford Csizmar: When It Comes to TET2 Mutations in CMML, More are Better
Jul 14, 2025, 16:48

Clifford Csizmar: When It Comes to TET2 Mutations in CMML, More are Better

Clifford Csizmar, Hematology and Oncology Fellow (PGY-5) at Mayo Clinic, shared a post on X:

“When it comes to TET2 mutations in CMML, more are better!

Multiple TET2 mt offset the negative impacts of ASXL1 and RAS mutations in myelodysplastic and myeloproliferative CMML, respectively.”

Title: Multiple TET2 mutations confer additional survival benefit in both myelodysplastic and myeloproliferative chronic myelomonocytic leukemia subtypes.

Authors: Clifford M. Csizmar, Anuya Natu, Mark Gurney, Saubia Fathima, Ali Khalid A. Alsugair, Rashmi Kanagal-Shamanna, Sanam Loghavi, Alexandre Bazinet, Kelly Chien, Danielle Hammond, Courtney DiNardo, Tapan Kadia, Farhad Ravandi-Kashani, Naveen Pemmaraju, Koji Sasaki, Terra L. Lasho, Christy M. Finke, Aref Al-Kali, Hassan Alkhateeb, Kebede Begna, Naseema Gangat, Mehrdad Hefazi Torghabeh, Aasiya Matin, Abhishek A. Mangaonkar, Antoine N. Saliba, Ayalew Tefferi, Guillermo Garcia-Manero, Hagop M. Kantarjian, Rami S. Komrokji, Zhuoer Xie, Najla A. Ali, David Sallman, Eric Padron, Guillermo Montalban-Bravo, Mrinal M. Patnaik

Read the Full Article on Leukemia

Clifford Csizmar: When It Comes to TET2 Mutations in CMML, More are Better

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