Science

Yüksel Ürün: Longitudinal ctDNA profiling in mCRPC reveals How Tumors Evolve

Yüksel Ürün/X

May 5, 2025, 12:30

Yüksel Ürün: Longitudinal ctDNA profiling in mCRPC reveals How Tumors Evolve

Yüksel Ürün, Medical Oncology professor at Ankara University School of Medicine, shared an article on X:

“Tracking resistance in real time:

Longitudinal ctDNA profiling in mCRPC reveals how tumors evolve.

Greater subclonal shifts seen with AR-targeted therapy vs taxanes.
Emerging clones enriched for PI3K-AKT alterations.”

Longitudinal Profiling of Circulating Tumor DNA Reveals the Evolutionary Dynamics of Metastatic Prostate Cancer during Serial Therapy.

Authors: Yuehui Zhao, Naveen Ramesh, Ping Xu, Emi Sei, Min Hu, Shanshan Bai, Patricia Troncoso, Ana M. Aparicio, Christopher J. Logothetis, Paul G. Corn, Nicholas E. Navin, Amado J. Zurita.

You can read the Full Article on Journal of American Association of Cancer Research.

Yüksel Ürün: Longitudinal ctDNA profiling in mCRPC reveals How Tumors Evolve

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