Robert Orlowski, Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared on X:
“Myeloma Paper of the Day:
Study of impact of GCSF on CRS during bispecific antibody initiation in RRMM finds trend towards increased risk but not significant (HR 1.7, 95% CI 0.6-4.7, p=0.3), suggesting G-CSF can be given for neutropenia w/ BsAbs.”
Title: Impact of granulocyte colony-stimulating factors on cytokine release syndrome during bispecific antibody initiation in relapsed/refractory multiple myeloma
Authors: Alice X. Wang, Tala Shekarkhand, David Nemirovsky, Andriy Derkach, Carlyn R. Tan, Issam S. Hamadeh, Ross S. Firestone, Eric Jurgens, Kevin Miller, Dhwani Patel, Neha Korde, Alexander M. Lesokhin, Sham Mailankody, Hani Hassoun, Hamza Hashmi, Sridevi Rajeeve, Urvi A. Shah, Kylee Maclachlan, Gunjan L. Shah, Michael Scordo, Heather J. Landau, Sergio A. Giralt, Saad Z. Usmani, Malin Hultcrantz
You can read the full article on Blood Cancer Journal.

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