Robert Orlowski, Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
Impaired microbial bile acid metabolism may add to Revlimid-related diarrhea, which is linked to reduced α-diversity and altered bacterial community composition, supporting microbiota-targeted strategies as mitigation.”
Title: Lenalidomide-Related Diarrhea in Patients with Multiple Myeloma is Associated with Gut Microbiota Dysbiosis and Disruption of the Bile Acid Pool
Authors: Kevin Charles Miller, Teng Fei, Ruben J. Faustino Ramos, Francesca Castro, Ana Gradissimo, Torin Block, Issam Hamadeh, Kylee H. Maclachlan, Malin L. Hultcrantz, Hani Hassoun, Sham Mailankody, Sridevi Rajeeve, Francesco Maura, Maximilian Merz, Hamza Hashmi, Ross Firestone, Eric Jurgens, Gunjan L. Shah, Michael Scordo, Heather J. Landau, Sergio A. Giralt, Neha Korde, Matthew J. Pianko, Saad Z. Usmani, Jonathan U. Peled, Urvi A. Shah, Alexander M. Lesokhin
You can read the Full Article on Clinical Cancer Research.
You can find other articles featuring Robert Orlowski on OncoDaily.
