Present Title & Affiliation
- Research Professor, Department of Paediatrics, The Chinese University of Hong Kong (2021–Present)
- Deputy Director (External), Hong Kong Hub of Paediatric Excellence, The Chinese University of Hong Kong (2018–Present)
- Honorary Consultant, Department of Paediatrics, Prince of Wales Hospital, Hong Kong (2016–Present)
- Honorary Consultant, Department of Paediatrics, Hong Kong Children’s Hospital (2019–Present)
- Cluster Coordinator (Paediatrics), New Territories East Cluster, Hospital Authority, Hong Kong (2016–Present)
PUBLICATIONS
- Books: Contributed chapters in 8 books, and served as Editor of one book.
- Journals: Author and co-author of 420 papers in peer-reviewed journals.
H-index: 54
Selected Publications
1. Zhang W, Cai J, Wang X, Ma Y, Zhu X, Yu J, Xiao P, Gao J, Fang Y, Liang C, Li X, Zhou F, Zhai X, Xu X, Tian X, Liu A, Wang N, Zhu J, Wang L, Cheng F.W.T., Yang L, Zhang G, Cheng C, Yang J.J., Shen S, Li C.K., Li B, Jiang H, Pui C.H.
Prognostic and therapeutic implications of measurable residual disease levels during remission induction of childhood ALL.
Blood. 2024 Dec 30; blood.2024026381. doi: 10.1182/blood.2024026381
2. Leung K.T., Cai J., Liu Y., Chan K.Y.Y., Shao J., Yang H., Hu Q., Xue Y., Wu X., Guo X., Zhai X., Wang N., Li X., Tian X., Li Z., Xue N., Guo Y., Wang L., Zou Y., Xiao P., He Y., Jin R., Tang J., Yang J.J., Shen S., Pui C.H., Li C.K.
Prognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in China.
Leukemia. 2023 Nov 25. doi: 10.1038/s41375-023-02089-3. PMID: 38001171
3. Leung A.W., Cai J., Wan Z., Qin J., Fang Y., Sun L., Zhu J., Hu S., Wang N., Gao P., Tian X., Zhu X., Zhou F., Wu X., Ju X., Zhai X., Jiang H., Hu Q., Liang C., Yang L., Zhang H., Tang J., Gao J., Pui C.H., Li C.K.
Outcome of infants with acute lymphoblastic leukemia treated with the Chinese Children’s Cancer Group Acute Lymphoblastic Leukemia 2015 study protocol.
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285201. PMID: 38634141
4. Li C.K., Kurkure P., Arora R.S., Chen B.W., Kirgizov K., Okamoto Y., Seksarn P., Tang Y., Yoo K.H., Agarwal B., Chan G.C.F., Dalvi R., Hori H., Khan M.S., Yu A., Nakagawara A.
Current Challenges of Asian National Children’s Cancer Study Groups on behalf of the Asian Pediatric Hematology and Oncology Group.
JCO Global Oncology. 2023 Sep;9:e2300153. doi: 10.1200/GO.23.00153. PMID: 37656946
5. He X., Zhang Z., Xue J., Wang Y., Zhang S., Wei J., Zhang C., Wang J., Urip B.A., Ngan C.C., Sun J., Li Y., Lu Z., Zhao H., Pei D., Li C.K., Feng B.
Low-dose AAV-CRISPR-mediated liver-specific knock-in restored hemostasis in neonatal hemophilia B mice with subtle antibody response.
Nature Communications. 2022 Nov 25;13(1):7275. doi: 10.1038/s41467-022-34898-y. PMID: 36434000
6. Wang H., Chan K.Y.Y., Cheng C.K., Ng M.H.L., Lee P.Y., Cheng F.W.T., Lam G.K.S., Chow T.W., Ha S.Y., Chiang A.K.S., Leung W.H., Leung A.Y.H., Wang C.C., Zhang T., Zhang X.B., So C.C., Yuen Y.P., Sun Q., Zhang C., Xu Y., Cheung J.T.K., Ng W.H., Tang P.M., Kang W., To K.F., Lee W.Y.W., Wong R.S., Poon E.N.Y., Zhao Q., Huang J., Chen C., Yuen P.M.P., Li C.K., Leung A.W.K., Leung K.T.
Pharmacogenomic profiling of pediatric acute myeloid leukemia to identify therapeutic vulnerabilities and inform functional precision medicine.
Blood Cancer Discovery. 2022; 3(6):516–535. doi: 10.1158/2643-3230.BCD-22-0011. PMID: 35960210
7. Tang J., Yu J., Cai J., Zhang L., Hu S., Gao J., Jiang H., Fang Y., Liang C., Ju X., Jin R., Zhai X., Wu X., Tian X., Hu Q., Wang N., Jiang H., Sun L., Leung A.W.K., Yang M., Pan K., Cheng C., Zhu Y., Zhang H., Li C., Yang J.J., Li C.K., Zhu X., Shen S., Pui C.H.
Prognostic factors for CNS control in children with acute lymphoblastic leukemia treated without cranial irradiation.
Blood. 2021 Jul 29;138(4):331–343. doi: 10.1182/blood.2020010438. PMID: 33684941
8. Yang W., Cai J., Shen S., Gao J., Yu J., Hu S., Jiang H., Fang Y., Liang C., Ju X., Wu X., Zhai X., Tian X., Wang N., Liu A., Jiang H., Jin R., Sun L., Yang M., Leung A.W.K., Pan K., Zhang Y., Chen J., Zhu Y., Zhang H., Li C., Yang J.J., Cheng C., Li C.K., Tang J., Zhu X., Pui C.H.
Pulse therapy with vincristine and dexamethasone for childhood acute lymphoblastic leukaemia (CCCG-ALL-2015): an open-label, multicentre, randomised, phase 3, non-inferiority trial.
Lancet Oncology. 2021 Sep;22(9):1322–1332. doi: 10.1016/S1470-2045(21)00328-4.
9. Shen S., Chen X., Cai J., Yu J., Gao J., Hu S., Zhai X., Liang C., Ju X., Jiang H., Jin R., Wu X., Wang N., Tian X., Pan K., Jiang H., Sun L., Fang Y., Li C.K., Hu Q., Yang M., Zhu Y., Zhang H., Li C., Pei D., Jeha S., Yang J.J., Cheng C., Tang J., Zhu X., Pui C.H.
Effect of Dasatinib vs Imatinib in the Treatment of Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Randomized Clinical Trial.
JAMA Oncology. 2020 Jan 16. doi: 10.1001/jamaoncol.2019.5868.
10. Leung K.T., Zhang C., Chan K.Y.Y., Li K., Cheung J.T.K., Ng M.H.L., Zhang X.B., Sit T., Lee W.Y.W., Kang W., To K.F., Yu J.W.S., Man T.K.F., Wang H., Tsang K.S., Cheng F.W.T., Lam G.K.S., Chow T.W., Leung A.W.K., Leung T.F., Yuen P.M.P., Ng P.C., Li C.K.
CD9 blockade suppresses disease progression of high-risk pediatric B-cell precursor acute lymphoblastic leukemia and enhances chemosensitivity.
Leukemia. 2020;34:709–720.
11. Pieters R., De Lorenzo P., Ancliffe P., Aversa L.A., Brethon B., Biondi A., Campbell M., Escherich G., Ferster A., Gardner R.A., Kotecha R.S., Lausen B., Li C.K., Locatelli F., Attarbaschi A., Peters C., Rubnitz J.E., Silverman L.B., Stary J., Szczepanski T., Vora A., Schrappe M., Valsecchi M.G.
Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study.
Journal of Clinical Oncology. 2019 Sep 1;37(25):2246–2256.