Massimo Di Maio: Standing Ovation for CHALLENGE phase 3 trial at ASCO25
Massimo Di Maio, Associate Professor of Medical Oncology at Department of Oncology, University of Turin, shared a post by NEJM on X, adding:
“Standing ovation for this trial at ASCO25 . Practice changing. The problem could be the adherence to physical exercise. Accrual in the trial was very slow, because many patients refused randomization to exercise, I suppose. Education is crucial.”
Quoting NEJM‘s post:
“Presented at ASCO25:
A 3-year structured exercise program after adjuvant chemotherapy for colon cancer improved disease-free and overall survival, physical functioning, and fitness, as compared with health education alone. Full CHALLENGE phase 3 trial results”
Title: Structured Exercise after Adjuvant Chemotherapy for Colon Cancer
Authors: Kerry S. Courneya, Janette L. Vardy, Christopher J. O’Callaghan, Sharlene Gill, Christine M. Friedenreich, Rebecca K.S. Wong, Haryana M. Dhillon, Victoria Coyle, Neil S. Chua, Derek J. Jonker, Philip J. Beale, Kamal Haider, Patricia A. Tang, Tony Bonaventura, Ralph Wong, Howard J. Lim, Matthew E. Burge, Stacey Hubay, Michael Sanatani, Kristin L. Campbell, Fernanda Z. Arthuso, Jane Turner, Ralph M. Meyer, Michael Brundage, Patti O’Brien, Dongsheng Tu, Christopher M. Booth
Read OncoDaily’s Special Articles about ASCO 2025:
Highlights from ASCO 2025 Day 1
Highlights from ASCO 2025 Day 2
Highlights from ASCO 2025 Day 3
Highlights from ASCO 2025 Day 4
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