Kristina Lindemann, Head of the Gynecological Oncology Center at Oslo University Hospital, shared a post on LinkedIn about a paper she co-authored with colleagues published in Gynecologic Oncology.
“New publication building on our ctDNA work in patients with endometrial cancer.
Happy to be part of this review summarizing the evidence on the prognostic value of preoperative ctDNA assessment.
Perioperative detection of ctDNA positivity is significantly associated with worse PFS and could serve as a valuable tool for EC prognostication and guidance for adjuvant therapy decision-making
More work is needed for clinical implementation, including longitudinal assessments as well as incorporating novel techniques for detection.”
Title: Prognostic value of perioperative circulating tumor DNA in endometrial cancer: systematic review and meta-analysis
Authors: Amna Ahmed, Gagandeep Saini, Sarah E. Ferguson, Rouhi Fazelzad, Qixuan Li, Kathy Han, Trevor Pugh, Derek Wong, Raymond H. Kim, Anjelica Hodgson, Samuel Leung, Amy Jamieson, Jessica N. McAlpine, Kristina Lindemann, Franziska Siegenthaler, and Soyoun Rachel Kim.
You can read the Full Article in Gynecologic Oncology.
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