Fabio Ynoe de Moraes Healthcare System
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Fabio Ynoe de Moraes: Why 95% of GenAI Pilots Die in Oncology and How to Be the 5% That Survive

Fabio Ynoe de Moraes, Radiation Oncologist and Associate Professor at Queen’s University, shared a post on LinkedIn:

GenAI in Oncology: Why most pilots die—and how to be the 5% that scales – lessons from other industries.

Hot take: GenAI isn’t failing because of ‘accuracy.’ It’s failing because it never survives the clinic.

In cancer care, extra portals = instant death. The winners redesign workflows, not just models.

Where GenAI already works (today):
  • Tumor boards → 60–90s longitudinal briefs with guideline snippets (clinician edits = learning).
  • Synoptic notes (RT/chemo) → draft + checklist verification of dose/fractions/OARs before sign-off.
  • Prior auth → payer-specific letters in minutes; track denial → approval lift.
  • Trial matching → I/E criteria parsed first; highlight exclusions to save time.
The 90-day rule:
  • One job to be done (e.g., −25% time/case).
  • Integrate into EHR/PACS/inbox—no new portal.
  • Guardrails: PHI off by default, provenance on, human-in-the-loop.
  • Measure absorption, not logins (how many steps did we delete?).
  • Scale only if the 30/60/90 gates are met.

If we design for the clinic—not the demo—oncology can be the sector that proves GenAI’s value this quarter, not ‘someday.’

Your turn: What single oncology workflow would you automate first—and what metric would you bet on?”

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