David Aggen: Investigating a Novel MMAE Binder to Prevent Enfortumab Vedotin-Associated Neuropathy in Metastatic Urothelial Cancer
David H Aggen/ Memorial Sloan Kettering Cancer Center/LinkedIn

David Aggen: Investigating a Novel MMAE Binder to Prevent Enfortumab Vedotin-Associated Neuropathy in Metastatic Urothelial Cancer

David Aggen, Assistant Attending at Memorial Sloan Kettering Cancer Center, shared a post on X:

“A major challenge for patients on Enfortumab Vedotin for prolonged periods is mitigating neuropathy.

We are actively investigating the use of a novel MMAE binder to prevent neuropathy for patients with metastatic urothelial cancer.

ESMO trial in progress poster.”

David Aggen: Investigating a Novel MMAE Binder to Prevent Enfortumab Vedotin-Associated Neuropathy in Metastatic Urothelial Cancer

You can also read: Phase Ib/II EV-103 at ESMO 2026: Long-Term Outcomes With Enfortumab Vedotin Plus Pembrolizumab in Advanced Urothelial Carcinoma

David Aggen: Investigating a Novel MMAE Binder to Prevent Enfortumab Vedotin-Associated Neuropathy in Metastatic Urothelial Cancer