Mark Lewis: Remember I before O

Mark Lewis shared on X:

“When using chemo regimens that contain both irinotecan and oxaliplatin, remember ‘I before O’ to reduce irinotecan-attributable cholinergic effects potentiated by oxaliplatin.”

Source: Mark Lewis/X

Mark Lewis is the Director of Gastrointestinal Oncology at Intermountain Healthcare in Utah, the Co-Chair of adolescent and young adult (AYA) oncology in the SWOG cooperative group, and the Vice President of American Multiple Endocrine Neoplasia Support. Dr. Lewis is also a well-known patient advocate and social media influencer.