Photo of Wafik S. El-Deiry from vivo.brown.edu
Mar 18, 2024, 09:48
Wafik S. El-Deiry: Important preliminary signal of transient response in GBM with CAR-T cells
Wafik S. El-Deiry, Director of the Legorreta Cancer Center at Brown University, shared a post on X:
“Important preliminary signal of transient response in GBM with CAR-T cells:
CAR T-Cell-Mediated Responses in Recurrent Glioblastoma.
First-in-human Intraventricular CARv3-TEAM-E T Cells that secrete T-cell–engaging antibody molecule (TEAM) and target EGFR vIII in Recurrent Glioblastoma
‘Radiographic tumor regression was dramatic and rapid, occurring within days after receipt of a single intraventricular infusion, but the responses were transient in two of the three participants. (Funded by Gateway for Cancer Research and others; INCIPIENT number, NCT05660369. opens in new tab.)”‘
Source: Wafik S. El-Deiry/X