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Jared Burks: Cancer-Induced Nerve Injury Drives Anti-PD-1 Resistance
Aug 23, 2025, 16:36

Jared Burks: Cancer-Induced Nerve Injury Drives Anti-PD-1 Resistance

Jared Burks, Director of the Innovation Nexus and Flow Cytometry and Cellular Imaging Core Facility at MD Anderson Cancer Center, shared a post on LinkedIn:

”I am excited to share that our latest research article, ‘Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy’, has been published in Nature.

This work uncovers a novel mechanism where cancer-induced nerve injury drives resistance to immunotherapy, specifically anti-PD-1 therapy. These insights open new possibilities for improving treatment responses in cancer patients facing immunotherapy resistance.

I want to thank all the incredible co-authors on this project, it is a numerous list, please check the publication, congrats Moran on getting this one complete!

Please check out the full publication here.”

Title: Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy

Authors: Erez N. Baruch, Frederico O. Gleber-Netto, Priyadharsini Nagarajan, Xiayu Rao, Shamima Akhter, Tuany Eichwald, Tongxin Xie, Mohammad Balood, Adebayo Adewale, Shorook Naara, Hinduja N. Sathishkumar, Shajedul Islam, William McCarthy, Brandi J. Mattson, Renata Ferrarotto, Michael K. Wong, Michael A. Davies, Sonali Jindal, Sreyashi Basu, Karine Roversi, Amin Reza Nikpoor, Maryam Ahmadi, Ali Ahmadi, Catherine Harwood, Irene Leigh, Dennis Gong, Paulino Tallón de Lara, Derrick L. Tao, Tara M. Davidson, Nadim J. Ajami, Andrew Futreal, Kunal Rai, Veena Kochat, Micah Castillo, Preethi Gunaratne, Ryan P. Goepfert, Sharia D. Hernandez, Nikhil I. Khushalani, Jing Wang, Stephanie S. Watowich, George A. Calin, Michael R. Migden, Mona Yuan, Naijiang Liu, Yi Ye, William L. Hwang, Paola D. Vermeer, Nisha J. D’Silva, Yuri L. Bunimovich, Dan Yaniv, Jared K. Burks, Javier Gomez, Patrick M. Dougherty, Kenneth Y. Tsai, James P. Allison, Padmanee Sharma, Jennifer A. Wargo, Jeffrey N. Myers, Sebastien Talbot, Neil D. Gross, Moran Amit

You can read the Full Article on Nature.

Jared Burks

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