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New Clinical Trial Explores WRN Helicase Inhibitor MOMA-341 in GI Cancers Resistant to Immunotherapy
Photo: Depositphotos
Aug 16, 2025, 11:26

New Clinical Trial Explores WRN Helicase Inhibitor MOMA-341 in GI Cancers Resistant to Immunotherapy

Tiago Biachi de Castria, Medical Oncologist, Associate Member at Moffitt Cancer Center, Associate Professor at University of South Florida, shared a post on LinkedIn:

“Phase 1 trial with MOMA-341 is now open at Moffitt (NCT06974110)! This is a potent WRN helicase inhibitor with great preclinical activity in MSI-H tumors and a great option for our GI cancers patients with primary or acquired resistance to IO.”

Read further.

WRN Helicase Inhibitor

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cancer Moffitt Cancer Center MOMA-341 OncoDaily Oncology Tiago Biachi de Castria University of South Florida WRN Helicase Inhibitor
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