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Rami Manochakian: Tarlatamab vs Chemotherapy in second treatment for advanced SCLC
Rami Manochakian/X
Jun 3, 2025, 09:56

Rami Manochakian: Tarlatamab vs Chemotherapy in second treatment for advanced SCLC

Rami Manochakian, Vice President of the North American Neuroendocrine Tumor Society, shared on X:

“Hot Off The Press!
Just published in NEJM in conjunction with presentation at ASCO 2025.
Results of DeLLphi304 phase trial of Tarlatamab vs Chemotherapy in 2nd treatment for advanced Small Cell Lung Cancer.
  • mOS: 13.6 vs 8.3 months (HR: 0.6)
  • More Improvement in symptoms with Tarlatamab
  • ≥ Grade 3 AEs: 54% vs 80%
  • CRS and ICANS mostly grade 1/2.”

Rami Manochakian: Tarlatamab vs Chemotherapy in second treatment for advanced SCLC

Read OncoDaily’s special articles:

Tarlatamab (Imdelltra): Uses in Cancer, Side Effects, Dosages, Expectations, and More

Tarlatamab (Imdelltra): What Patients Need to Know About

ASCO 2025 cancer DeLLphi304 trial OncoDaily Oncology Rami Manochakian SCLC Tarlatamab
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