Arndt Vogel/X
Jun 1, 2025, 00:32
Arndt Vogel: 1st line encorafenib + cetuximab + mFOLFOX6 vs SOC in BRAF V600E-mCRC
Arndt Vogel, Managing Senior Consultant and a Professor in the Department of Gastroenterology, Hepatology, and Endocrinology at Hannover Medical School, posted on X:
“1st line encorafenib + cetuximab + mFOLFOX6 vs SOC in BRAF V600E-mCRC
BREAKWATER: PFS + updated OS
ASCO25
ORR 65 vs 37 vs 43 %
mPFS 12.8 vs 7.1 vs 6.9 mo
mOS 30.3 vs 15.1 vs 19.1 mo
AE ≥3 76% vs 58 vs 15.7%
Really effective, new SOC in 1st line.”
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