Samuel Hume: Top 5 advances in medicine this week
Samuel Hume, Fellow at The Foulkes Foundation and pursuing PhD in the University of Oxford’s Department of Oncology, shared a post on X:
“Top 5 advances in medicine this week
1. A new first-line option for liver cancer (FDA-approved)
2. A new medication to cut cholesterol (Phase 3 trial)
3. A possible emerging therapy for ALS (Phase 2b trial)
4. Updated CAR-T cells for lymphoma (Phase 1 trial)
5. Google’s AI beats doctors (again) (RCT)
1. A new first-line option for liver cancer
Title: Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first-line treatment for unresectable hepatocellular carcinoma (CheckMate 9DW): an open-label, randomised, phase 3 trial
Journal: The Lancet
Authors: Thomas Yau, Peter R. Galle, Thomas Decaens, Bruno Sangro, Shukui Qin, Leonardo G. da Fonseca, Hatim Karachiwala, Jean-Frederic Blanc, Joong-Won Park, Edward Gane, Matthias Pinter, Ana Matilla Peña, Masafumi Ikeda, David Tai, Armando Santoro, Gonzalo Pizarro, Chang-Fang Chiu, Michael Schenker, Aiwu He, Hong Jae Chon, Joanna Wojcik-Tomaszewska, Gontran Verset, Qi Qi Wang, Caitlyn Stromko, Jaclyn Neely, Prianka Singh, Maria Jesus Jimenez Exposito, Masatoshi Kudo
2. A new medication to cut cholesterol
Title: Fixed-dose combination of obicetrapib and ezetimibe for LDL cholesterol reduction (TANDEM): a phase 3, randomised, double-blind, placebo-controlled trial
Journal: The Lancet
Authors: Ashish Sarraju, Danielle Brennan, Kierstyn Hayden, Amanda Stronczek, Anne C. Goldberg, Erin D. Michos, Darren K. McGuire, Denise Mason, Grace Tercek, Stephen J. Nicholls, Douglas Kling, Annie L. Neild, John Kastelein, Michael Davidson, Marc Ditmarsch, Steven E. Nissen
3. A possible emerging therapy for ALS
Title: Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial
Journal: The Lancet
Authors: Gilbert Bensimon, P Nigel Leigh, Timothy Tree, Andrea Malaspina, Christine AM Payan, Hang-Phuong Pham, Pieter Klaassen, Pamela J Shaw, Ahmad Al Khleifat, Maria D M Amador, Shahram Attarian, Simon M Bell, Stéphane Beltran, Emilien Bernard, William Camu, Philippe Corcia, Jean-Christophe Corvol, Philippe Couratier, Véronique Danel, Rabab Debs, Claude Desnuelle, Aikaterini Dimitriou, John Ealing, Florence Esselin, Marie-Céline Fleury, George H Gorrie, Aude-Marie Grapperon, Adèle Hesters, Raul Juntas-Morales, Ivan Kolev, Géraldine Lautrette, Nadine Le Forestier, Christopher J McDermott, Nicolas Pageot, François Salachas, Nikhil Sharma, Marie-Hélène Soriani, Jemeen Sreedharan, Juliette Svahn, Nick Verber, Annie Verschueren, Ozlem Yildiz, Carey M Suehs, Safaa Saker-Delye, Claudie Muller, Christophe Masseguin, Hana Hajduchova, Janine Kirby, Cecilia Garlanda, Massimo Locati, Henrik Zetterberg
4. Updated CAR-T cells for lymphoma
Title: Enhanced CAR T-Cell Therapy for Lymphoma after Previous Failure
Journal: The New England Journal of Medicine
Authors: Jakub Svoboda, Daniel J. Landsburg, James Gerson, Sunita D. Nasta, Stefan K. Barta, Elise A. Chong, Michael Cook, Noelle V. Frey, Joanne Shea, Amanda Cervini, Amy Marshall, Megan Four, Megan M. Davis, Julie K. Jadlowsky, Anne Chew, Edward Pequignot, Vanessa Gonzalez, Julia Han Noll, Luca Paruzzo, Juliana Rojas-Levine, Gabriela Plesa, John Scholler, Donald L. Siegel, Bruce L. Levine, David L. Porter, Saba Ghassemi, Marco Ruella, Andrew Rech, Rachel M. Leskowitz, Joseph A. Fraietta, Wei-Ting Hwang, Elizabeth Hexner, Stephen J. Schuster, Carl H. June
5. Google’s AI beats doctors (again)”
Title: Advancing Conversational Diagnostic AI with Multimodal Reasoning
Authors: Khaled Saab, Jan Freyberg, Chunjong Park, Tim Strother, Yong Cheng, Wei-Hung Weng, David G.T. Barrett, David Stutz, Nenad Tomasev, Anil Palepu, Valentin Liévin, Yash Sharma, Roma Ruparel, Abdullah Ahmed, Elahe Vedadi, Kimberly Kanada, Cian Hughes, Yun Liu, Geoff Brown, Yang Gao, Sean Li, S. Sara Mahdavi, James Manyika, Katherine Chou, Yossi Matias, Avinatan Hassidim, Dale R. Webster, Pushmeet Kohli, S.M. Ali Eslami, Joëlle Barral, Adam Rodman, Vivek Natarajan, Mike Schaekermann, Tao Tu, Alan Karthikesalingam, Ryutaro Tanno
More posts featuring Samuel Hume on OncoDaily.
-
Challenging the Status Quo in Colorectal Cancer 2024
December 6-8, 2024
-
ESMO 2024 Congress
September 13-17, 2024
-
ASCO Annual Meeting
May 30 - June 4, 2024
-
Yvonne Award 2024
May 31, 2024
-
OncoThon 2024, Online
Feb. 15, 2024
-
Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023