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Aaron Goodman: Mature B-cell Leukemias
Jan 11, 2025, 14:01

Aaron Goodman: Mature B-cell Leukemias

Aaron Goodman, Hematologist/Oncologist and an Associate Professor of Medicine at the University of California, shared a post on X:

“Mature B-cell Leukemias my favorite ddx!

Classify by CD5/CD10

CD5+/CD10-:
CLL = CD23+
Leukemic mantle cell = CD23-

CD5-/CD10-:
Hairy cell leukemia = CD11c+, CD123+, BRAF+
HCLv/PLL = CD11c+, CD123-, BRAF-
SMZL = HCV, del7q31, MYD88 (subset)

CD5-/CD10+: Leukemic follicular.”

Aaron Goodman: Mature B-cell Leukemias