Nov 8, 2024, 15:14
Toby Eyre: R-Ibrutinib vs R-chemo as first line for Metastatic Cell Lymphoma
Toby Eyre, Specialist in Lymphoma CLL and Senior lecturer in University of Oxford, shared the post on X:
“ENRICH Primary analysis.
-4y follow up
-R-Ibrutinib vs R-chemo (BR or RCHOP) 1L MCL
-IR superior PFS to ICT HR 0.69 p=0.003
-Low haem toxicity
-Earlier increased QoL with R-Ibr
-Major benefit seen vs RCHOP subgroup
-1st 1L RCT across any lymphoma (not included CLL) showing non-chemo superior to ICT.”
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