Association between TIL and survival in patients with MBC receiving first-line chemotherapy

Elisabetta Bonzano, Radiation Oncologist at IRCCS San Matteo Polyclinic Foundation, shared a paper by Daniel Stover et al. on X, adding:

“Association between tumor-infiltrating lymphocytes and survival in patients with metastatic breast cancer receiving first-line chemotherapy: analysis of CALGB 40502.

• To evaluate the association of sTILs with progression-free survival in randomized phase III trial CALGB 40502.
• sTILs were associated with progression-free and overall survival in chemotherapy-treated MBC when controlling for treatment arm; however, this effect did not remain significant after additional adjustment for hormone receptor status.”

Source: Elisabetta Bonzano/X

Association between tumor-infiltrating lymphocytes and survival in patients with metastatic breast cancer receiving first-line chemotherapy: analysis of CALGB 40502.

Authors: Daniel G. Stover, Roberto Salgado, Oleksander Savenkov, Karla Ballman, Erica L. Mayer, Mark Jesus M. Magbanua, Sherene Loi, Mark Vater, Kristyn Glover, Mark Watson, Yujia Wen, W. Fraser Symmans, Charles Perou, Lisa A. Carey, Ann H. Partridge and Hope S. Rugo.