Science

Rahul Banerjee/fredhutch.org

Jul 6, 2025, 15:22

Rahul Banerjee: Off-the-Shelf In Vivo BCMA CAR-T in Myeloma Hits The Lancet

Rahul Banerjee, Assistant Professor at Fred Hutchinson Cancer Center at the University of Washington, shared a post on X about a paper by Jia Xu et al. published in The Lancet:

“Now in big The Lancet – in vivo BCMA CAR in myeloma!

Off the shelf in a big way – clever design as low including don’t-eat-me and CD47 knockdown.

4 patients who received this did well; most had Gr3 CRS. Circulating out in 48 hours, peak at D10-17.

Exciting to see!”

Title: In-vivo B-cell maturation antigen CAR T-cell therapy for relapsed or refractory multiple myeloma

Authors: Jia Xu, Lin Liu, Philippe Parone, Wei Xie, Chunyan Sun, Zhaozhao Chen, Jishuai Zhang, Chunrui Li, Yu Hu, Heng Mei.

You can read the Full Article in The Lancet.

Rahul Banerjee: Off-the-Shelf In Vivo BCMA CAR-T in Myeloma Hits The Lancet

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