Giannis Mountzios, Director of the 4th Oncology Department and Clinical Trials Unit at Henry Dunant Hospital Center, shared on X:
“Α very provocative study in Journal of Clinical Oncology in patients with ES-SCLC with brain-only-progression on 1L chemoIO shows that continuing the same systemic treatment (ST) and adding SBRT/RT improves OS compared to switching ST +SBRT/RT. Always treat the sanctuary and preserve the backbone!”
Title: Multicenter Cohort Study of Original or Substitute Systemic Therapy With or Without Brain Radiotherapy for Extensive-Stage Small Cell Lung Cancer With Brain-Only Progression After First-Line Treatment
Authors: Shuangqing Lu, Jingyi Jia, Kai Ren, Wenxiao Jia, Zhuoran Sun, Ke Zhao, Xuwei Cai, Lujun Zhao, Hui Zhu
Phase 2 Study Evaluates BIO 300 With SBRT in Early-Stage NSCLC and ILD