Journal of Clinical Oncology

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November, 2024
November 2024
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Journal of Clinical Oncology
Nov 13, 2024, 08:51 | Insight
Reporting pharmacogenetic variants and cancer WGS data could guide safer prescribing
Ben Westphalen, Oncologist with a specialization in Precision Oncology and Serving as chair of the…
Nov 11, 2024, 03:48 | Insight
Trastuzumab Deruxtecan in Advanced Solid Tumors With HER 2 Amplification Identified
Arndt Vogel, Managing Senior Consultant and a Professor in the Department of Gastroenterology, shared an…
Nov 10, 2024, 14:56 | Blog
Pamela Kunz: Disrupting GI Oncology: Shattering Barriers with Inclusive Science
Pamela Kunz, Director of the Center for Gastrointestinal Cancers at Yale Cancer Center, shared a post…
Nov 10, 2024, 03:29 | Insight
Harold J. Burstein: Anthracyclines in Early Breast Cancer - The Long Goodbye
Harold J. Burstein, Breast Cancer Specialist and Professor at Harvard Medical School, shared a recent…
Nov 9, 2024, 15:58 | Insight
Addition of Metastasis-Directed Therapy to Systemic Therapy for Oligometastatic PDAC
Arndt Vogel, Professor in the Department of Gastroenterology, Hepatology, and Endocrinology at Hannover Medical School,…
Nov 7, 2024, 14:53 | Career
Rana McKay - Candidate for ASCO Nominating Committee
Rana McKay has been nominated as the Undesignated Member Candidate of the nomination committee for…
Nov 1, 2024, 17:31 | Insight
Francisco Esteva: ADCs are making waves in the fight against advanced HER2+ breast cancer
Francisco Esteva, Chief of the Division of Hematology and Medical Oncology at Lenox Hill Hospital,…
Oct 26, 2024, 10:44 | Blog
Laura Vater: JCO podcast about grief and the power of colleagues who support one another
Laura Vater, Gastrointestinal oncologist at the IU Simon Comprehensive Cancer Center, shared a post on…
Oct 25, 2024, 14:25 | Insight
Aaron Mitchell: New findings on cancer care quality for low-income Medicare patients
Aaron Mitchell, Medical Oncologist and Health Services Researcher at Memorial Sloan Kettering Cancer Center, shared…
Oct 16, 2024, 14:49 | Blog
Oncology Accelerated Approval Confirmatory Trials - FDA
FDA posted on LinkedIn about recent paper by Gautam Mehta and Richard Pazdur, titled "Oncology Accelerated Approval…
Oct 16, 2024, 08:41 | Blog
Gertjan Rasschaert: Salvage surgery for unifocal metastatic dMMR GI cancer responding to ICI
Gertjan Rasschaert posted on LinkedIn about recent paper by him as co-author, titled "Salvage Surgery…
Oct 15, 2024, 16:40 | Insight
First-Line Procarbazine, CCNU, and Vincristine With Radiotherapy in IDH-Mutant Oligodendroglioma - Journal of Clinical Oncology
Journal of Clinical Oncology shared a post on X: "Survival Outcomes Associated With First-Line Procarbazine, CCNU,…
Oct 11, 2024, 17:58 | Insight
Jarushka Naidoo: Randomized Phase II Trial Osimertinib with or without Ramucirumab in 1st line EGFR+NSCLC
Jarushka Naidoo shared a post on X: "RAMOSE: Randomized Ph II Trial Osimertinib+/-Ramucirumab in 1L EGFR+…
Oct 11, 2024, 17:21 | Insight
Xiuning Le: Phase 2 RAMOSE osimertinib with or without ramucrimab in 1L EGFR+ NSCLC
Xiuning Le shared a post on X: "Newly online Journal of Clinical Oncology. Our randomized phase…
Oct 11, 2024, 16:32 | Blog
Jarushka Naidoo: Patient Enrollment to Industry vs Federally-funded Cancer Clinical Trials
Jarushka Naidoo shared a post on X, about recent paper published in Journal of Clinical…
Oct 9, 2024, 16:50 | Insight
Ghassan Abou-Alfa: ERBB2-altered gallbladder cancer characterization in Chile
Ghassan Abou-Alfa, Medical Oncologist, Memorial Sloan Kettering Cancer Center, shared a post on X: "Congratulations…
Oct 8, 2024, 15:41 | Insight
Elisa Agostinetto: Association between hormonal contraceptives and breast cancer risk in BRCA1 carriers
Elisa Agostinetto shared a post on X: “Out in Journal of Clinical Oncology: A pooled…
Oct 8, 2024, 12:58 | Blog
Maryam Lustberg: Diverse site participation is needed to promote equitable access to trials
Maryam Lustberg posted on LinkedIn about recent paper by M. Kelsey Kirkwood et al., titled…
Oct 5, 2024, 17:01 | Blog
Erman Akkus: Local therapy in oligometastatic pancreatic cancer
Erman Akkus posted on X about recent paper by Hannah J. Roberts et al., titled…
Oct 5, 2024, 08:28 | Insight
Ryan Nipp: Delivering High-Quality Cancer Care
Ryan Nipp shared a post on X about a recent paper by Larissa Nekhlyudov et…
Oct 4, 2024, 15:14 | Blog
Evolving Landscape of Metastatic Cancer Survivorship
Maryam Lustberg posted on X about recent paper by Julia Lai-Kwon et al., titled "Evolving…
Oct 3, 2024, 17:40 | Blog
Honoring Dr Stella Arakelyan and welcoming Dr Mark Lawler as ICC's New Research Lead
The Institute of Cancer and Crisis (ICC) shared a post on LinkedIn, adding: " On…
Oct 2, 2024, 15:22 | Blog
We are Physicians, and the interest of patients should be our priority, summarised by Yakup Ergün
Yakup Ergün, Medical Oncologist at Bower Hospital, shared an article by Fred Saad on X:…
Sep 29, 2024, 18:45 | Insight
Ishwaria Subbiah: Understanding what goal concordant care truly means
Ishwaria Subbiah shared a post on LinkedIn: "Goal-Concordant Care Now out in Journal of Clinical Oncology …
Sep 29, 2024, 15:43 | Blog
Paolo Tarantino: The ratio of enrollment to industry-sponsored trials has doubled between 2008-2022
Paolo Tarantino shared the following on X: “Out in JCO: the ratio of enrollment to…
Sep 27, 2024, 13:26 | Blog
Yara Abdou: Navigating Treatment pathways in Metastatic HR+ Breast cancer
Yara Abdou shared a post on X: "With the expanding arsenal of endocrine & targeted…
Sep 26, 2024, 15:41 | Blog
Mark Lewis: The 'trolley problem' of adjuvant chemotherapy in colon cancer
Mark Lewis shared a post on X, about paper published in Journal of Clinical Oncology:…
Sep 26, 2024, 15:35 | Blog
Jarushka Naidoo: TL01 Phase III Datopotamab-Deruxtecan vs Docetaxel in second-line NSCLC
Jarushka Naidoo shared a post on X, about recent paper published in Journal of Clinical…
Sep 25, 2024, 14:44 | Blog
Tim Clay: Discussing fertility always matters
Tim Clay posted on X about recent paper by Margaret Cupid-Link, titled "It Mattered Later:…
Sep 24, 2024, 11:46 | Blog
David Palma: Final results of ORATOR, after completion of the full follow-up period
David Palma shared a post on X, about recent paper published in Journal of Clinical…
Sep 23, 2024, 14:23 | Insight
Stephanie Graff: What ‘clinically meaningful’ actually means
Stephanie Graff shared on LinkedIn: “We have all heard the phrase ‘clinically meaningful’ from the…
Sep 21, 2024, 00:15 | Blog
NLP is a feasible approach to measuring quality of care for children with cancer at end of life
Yale Cancer Center shared a post on X, about recent paper published in Journal of…
Sep 20, 2024, 18:44 | Blog
Alberto Puccini: Our Correspondence to the new ASCO Guidelines on the "Selection of germline genetic testing panels in patients with cancer"
Alberto Puccini, Medical Oncologist at Humanitas Cancer Center at Milan, Italy, posted on LinkedIn about…
Sep 18, 2024, 23:22 | Insight
Stephen Liu: Update from TROPION-Lung01
Stephen Liu shared a post on X: “Update from TROPION-Lung01 presented at WCLC24 and now Journal…
Sep 17, 2024, 10:06 | Insight
Sumanta K. Pal: Important analysis of SWOG 1500 published just ahead of ESMO24
Sumanta K. Pal shared a post on X: "Huge congrats to Pedro C Barata, who drove…
Sep 15, 2024, 12:53 | Blog
Sumanta Pal's highlights from ESMO24
The ESMO Congress 2024 is ongoing in Barcelona, from September 13 to 17, 2024, at the…
Sep 13, 2024, 15:01 | Insight
Piotr Wysocki: IPMN-derived pancreatic cancer patients benefit from adjuvant chemotherapy only with nodal involvement and elevated preoperative CA19-9
Piotr Wysocki recently shared a post on LinkedIn: "A recent international multicenter study published in…
Sep 12, 2024, 15:37 | Insight
Bertrand Tombal: Do Not EMBARK on When, If the Answer Is How
Bertrand Tombal, Chairman, Department of Surgery, Cliniques universitaires Saint-Luc, shared a post on X: "The…
Sep 11, 2024, 16:34 | Insight
Andrea Necchi: Our next piece of the neoadjuvant puzzle in muscle-invasive bladder cancer
Andrea Necchi, Associate Editor at Journal of Clinical Oncology, shared a post on X about…
Sep 11, 2024, 08:57 | Insight
TROPION-Lung01 Presents Further Data on Dato-DXd for NSCLC at WCLC - ASCO
American Society of Clinical Oncology (ASCO) shared a post on LinkedIn: "Lung Cancer Study (TROPION-Lung01)…
Sep 11, 2024, 06:09 | Blog
Vivek Subbiah: First-in human phase 1 dose-escalation study of BT5528 in Patients With Advanced Solid Tumors
Vivek Subbiah shared a post on X: "Hot of the press - Pleased to share our…
Sep 11, 2024, 01:59 | Societies
38 Posts Not to Miss From WCLC24 Day 3!
The WCLC24 is taking place at the San Diego Convention Center from September 7 to…
Sep 10, 2024, 13:45 | Societies
Rami Manochakian's key highlights from WCLC24
WCLC is a major international event focused on the latest advancements in lung cancer research,…
Sep 8, 2024, 16:13 | Insight
Tomas G. Neilan: Can large language models outperform ICD codes in detecting severe immune-related adverse events?
Tomas G. Neilan, Director of the Cardio-Oncology Program at Massachusetts General Hospital, shared on X:…
Sep 7, 2024, 19:36 | Insight
A year of treatment with an ADC has proven highly effective in preventing stage 1 HER2-positive breast cancer from recurring - Dana-Farber Cancer Institute
Dana-Farber Cancer Institute shared the following on LinkedIn: “A year of treatment with a medicine…
Sep 6, 2024, 12:30 | Career
Mikkael A. Sekeres, Candidate for Secretary of ASH
Mikkael A. Sekeres, Chair of Committee on Communications at American Society of Hematology (ASH) is…
Sep 4, 2024, 06:42 | Insight
Layth Mula-Hussain: Where does the MENAT region stand in radiation oncology
Layth Mula-Hussain shared on LinkedIn: “Delighted to be part of this recently ASCO JCO GO…
Sep 2, 2024, 03:14 | Insight
Othman Al-Sawaf: Surrogacy of endpoints in 1L CLL trials
Othman Al-Sawaf, Haematologist and Medical Oncologist at the University Hospital Cologne, Cologne, Germany, shared a…
Sep 1, 2024, 20:21 | Blog
Andrea Necchi: MRI should be a routine for daily management of MIBC
Andrea Necchi, Associate Editor at Journal of Clinical Oncology, shared Nick James's, Professor of Prostate…
Sep 1, 2024, 08:30 | Insight
Sacituzumab Govitecan in cisplatin-ineligible metastatic urothelial cancer after CPI
TROPHY-U-01 Cohort 2: A Phase II Study of Sacituzumab Govitecan in Cisplatin-Ineligible Patients With Metastatic…
Aug 31, 2024, 09:45 | Insight
Piotr Wysocki: Older patients with mCRC receiving fluoropyrimidine+bevacizumab do not gain additional benefit from adding oxaliplatin
Piotr Wysocki recently shared on LinkedIn: "A recent phase III clinical trial published in the…
Aug 25, 2024, 14:15 | Insight
JCO Study Confirms Annual Mammograms Improve Breast Cancer Outcomes Across All Demographics
American Society of Clinical Oncology (ASCO) shared a post on LinkedIn about a recent paper…
Aug 22, 2024, 20:35 | Insight
Oral Cannabis for Secondary Prevention of Chemotherapy-Induced Nausea and Vomiting
The final results of the study on Oral Cannabis Extract for the secondary prevention of…
Aug 22, 2024, 15:06 | Insight
Elias Karam: The ultimate dilemma of corticosteroids and Immunotherapy
Elias Karam, Hematology and Medical Oncology Fellow at Gustave Roussy, shared a post on LinkedIn about…
Aug 20, 2024, 16:41 | Insight
Elvina Almuradova: Metastasis-free or treatment-free survival
Elvina Almuradova, Medical Oncologist Ambassador at European School of Oncology, shared a post on X about…
Aug 19, 2024, 11:57 | Insight
Katsuaki Maehara: Interesting indirect comparison analysis for Melanoma
Katsuaki Maehara shared a post on X: "Melanoma Journal of Clinical Oncology. NCCN Guidelines recommended both…
Aug 19, 2024, 10:18 | Insight
Ryan Nipp: Oral Cannabis Extract for Secondary Prevention of Chemotherapy-Induced Nausea and Vomiting
Ryan Nipp, Oncologist at University of Oklahoma, shared on X a recent article published in Journal…
Aug 18, 2024, 07:29 | Blog,Opinion
Paolo Tarantino: Do all patients with TNBC need 5 neoadjuvant drugs + 1 year of IO?
Paolo Tarantino shared a post on X about recent paper by Marleen Kok et al., titled…
Aug 14, 2024, 06:28 | Insight
Myriam Chalabi: Management of Locally Advanced Rectal Cancer: - ASCO Guideline
Myriam Chalabi shared on X: "Now online in the Journal of Clinical Oncology! Management of…
Aug 13, 2024, 18:32 | Blog
Nathan Pennell: Such an important statement to reduce administrative burden on research sites
Nathan Pennell, Professor and Vice Chair of Clinical Research at Cleveland Clinic, shared a post…
Aug 12, 2024, 21:46 | Blog
GI cancers - rapid oral abstracs in ASCOBT 24 summarized by Erman Akkus
Erman Akkus, Medical Oncology Fellow at Ankara University Faculty of Medicine, shared on X: "GI…
Aug 12, 2024, 20:58 | Insight
Post-transplant maintenance for AML: Review of literature by Talha Badar
Talha Badar shared a post on X: "Post transplant maintenance for AML. How should you…
Aug 12, 2024, 04:06 | Blog
Akihiro Ohba: Trastuzumab Deruxtecan in HER 2–Expressing Biliary Tract Cancer
Akihiro Ohba, Medical Oncologist at Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital,…
Aug 11, 2024, 12:56 | Insight
Trastuzumab Deruxtecan in HER2–Expressing BTC - Key points by Arndt Vogel
Arndt Vogel shared a post on X: "Trastuzumab Deruxtecan in HER2–Expressing BTC published in  Journal of…
Aug 11, 2024, 12:18 | Insight
Jordan Hansford: The importance of rigorous trials with "new" and novel agents
Jordan Hansford, McClurg Brain Cancer Fellow at SAHMRI, shared on X about a recent paper…
Aug 11, 2024, 11:59 | Blog
Myriam Chalabi: Management of Locally Advanced Rectal Cancer, ASCO Guidelines
Myriam Chalabi, Medical Oncologist at The Netherlands Cancer Institute, shared a post on X about…
Aug 11, 2024, 10:29 | Blog
The intratumoral microbiome in lung cancer
Sumanta K. Pal shared a post on X: "HUGE congrats to Arielle Elkrief, Smruthy Sivakumar, Marc…
Aug 10, 2024, 15:51 | Insight
Steroids for irAEs and ICI efficacy: analysis from 6 trials
Jarushka Naidoo shared a post on X about a recent paper by Karijn Suijkerbuijk et…
Aug 10, 2024, 12:57 | Insight
MD Anderson Research Highlights
Featuring cell biology insights, new targets to prevent dysphagia, improved treatments for advanced cancers and…
Aug 9, 2024, 02:19 | Blog
Activity of T-DXd in HER2-expressing Biliary Tract Cancer
Paolo Tarantino shared on X: "Activity of T-DXd in HER2-expressing BTC published in Journal of Clinical…
Aug 8, 2024, 12:35 | Blog
Miguel Bronchud: Liquid biopsy to detect early breast cancers
Miguel Bronchud, Co-Founder and Advisory Board at Regenerative Medicine Solutions, shared a post on LinkedIn,…
Aug 8, 2024, 01:43 | Insight
Adding metastasis-directed radiation therapy boosts progression-free survival in metastatic pancreatic cancer - MD Anderson Cancer Center 
Approach achieves some of the longest progression-free survival times reported in a clinical trial for…
Aug 7, 2024, 16:01 | Insight
Piotr Wysocki: Trastuzumab Deruxtecan Shows Promise in Treating HER2-Positive Biliary Tract Cancer
Piotr Wysocki recently shared on LinkedIn: "A recent phase II clinical trial conducted across five…
Aug 6, 2024, 14:09 | Blog
DeepHRD predicts HRD from routine biopsy slides
Elvina Almuradova, Medical Oncologist Ambassador at European School of Oncology, shared a post on X,…
Aug 4, 2024, 23:39 | Insight
HERALD EPOC1806 study explores trastuzumab deruxtecan in solid tumors with HER2 amplification by ctDNA
Stephen Liu shared a post on X: "HERALD EPOC1806 study published in JCO explored trastuzumab…
Aug 2, 2024, 01:47 | Blog
Sergio Cifuentes Canaval: Neoadjuvant Chemo-Immuno for ER+ HER- breast cancer
Sergio Cifuentes Canaval, Cancer Research Project Manager at CENEIT Mexico, shared on LinkedIn about recent…
Jul 30, 2024, 06:39 | Insight
Ph II KUPENG trial of Vebreltinib in Advanced MetExon14 and NSCLC
Jarushka Naidoo shared a post on X about a recent paper by Jin-Ji Yang et…
Jul 30, 2024, 01:45 | Insight
TKIs with vs without upfront SRS for EGFR+ and ALK+ NSCLC and brain metastasis
Biagio Ricciuti shared on X about a recent paper by Luke Pike et al. titled…
Jul 27, 2024, 14:57 | Insight
Edward Cliff: The development and clinical trial design of T-cell lymphoma drugs pralatrexate and belinostat
Edward Cliff, Haematology Registrar at Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, shared a…
Jul 27, 2024, 13:30 | Insight
Piotr Wysocki: Impact of genomic risk on response to extended adjuvant endocrine therapy
Piotr Wysocki recently posted on LinkedIn: "A recent study published in the Journal of Clinical Oncology…
Jul 25, 2024, 14:02 | Insight
Erman Akkus: Should up-front SRS be added to TKI in brain metastatic EGFR/ALK positive NSCLC?
Erman Akkus, Medical Oncologist at Ankara University, shared a paper by Luke R.G. Pike et al. on…
Jul 25, 2024, 08:58 | Insight
Marleen Kok: How do we get from one-size-fits-all to personalized treatment for TNBC
Marleen Kok, Breast Medical Oncologist at the Netherlands Cancer Institute, shared on X: "Today from…
Jul 22, 2024, 02:26 | Insight
New Chapter in Ewing Sarcoma Treatment - The story of TK216
Shushan Hovsepyan shared a post on LinkedIn about a recent paper by Paul Meyers et…
Jul 21, 2024, 15:37 | Insight
Neoadjuvant osimertinib for resectable EGFR NSCLC
Stephen V Liu shared on X a recent paper by Collin M. Blakely et al.…
Jul 21, 2024, 13:36 | Blog
Rami Manochakian: Neoadjuvant osimertinib in stage I-IIIA EGFRm NSCLC did not meet primary endpoint
Rami Manochakian shared a post on X: ''Hot off the press. Neoadjuvant Osimertinib for the…
Jul 20, 2024, 22:54 | Blog
David S. Miller: Why Cisplatin should not be added to radiotherapy for certain recurrent Endometrial Cancer
David Scott Miller, Gynaecologic Oncologist and Professor at Department of Obstetrics and Gynaecology at UT…
Jul 20, 2024, 12:53 | Insight
Cyclophosphamide–Based GVHD Prophylaxis Reduces Outcome Disparity in Transplants
CIBMTR shared a post on X about a recent paper.  . Authors: Brian C. Shaffer,…
Jul 19, 2024, 13:20 | Blog
Alexios Matikas: We show for the first time the superiority of dose dense versus Standard Adjuvant Chemotherapy for High-Risk Early Breast Cancer
Alexios Matikas, Associate Professor of Oncology at Karolinska Institute, shared on LinkedIn: "Dose dense is…
Jul 18, 2024, 10:41 | Insight
Systemic Therapy in Breast Cancer
Erman Akkus, Medical Oncology Fellow at Ankara University Faculty of Medicine, shared on X about…
Jul 17, 2024, 23:36 | Blog
Ishwaria Subbiah: Discussion on dissemination of evidence-based care of older adults with cancer with CARG
Ishwaria Subbiah shared on LinkedIn: "Superb discussion within our Cancer and Aging Research Group (CARG) core…
Jul 17, 2024, 21:52 | Blog
Ishwaria Subbiah: Superb discussion on dissemination of evidence-based care of older adults with cancer
Ishwaria Subbiah shared a post on X: ''Superb discussion within our Cancer and Aging Research…
Jul 16, 2024, 13:55 | Blog
5 papers to read suggested by Vivek Subbiah
We are presenting articles suggested by Vivek Subbiah: 1.'Pancreatic Cancer Surveillance and Survival of High-Risk…
Jul 13, 2024, 22:16 | Insight
Erman Akkus: Management of cancer-related fatigue - ASCO guideline
Erman Akkus, Medical Oncology Fellow at Ankara University, shared a post on X about a…
Jul 9, 2024, 07:25 | Insight
Piotr Wysocki: Checkpoint inhibitor and TKI combinations in GU malignancies
Piotr Wysocki recently posted on LinkedIn: "A phase I study (Apolo AB et al. J Clin…
Jul 8, 2024, 14:29 | Blog
Shahrin Ahmed: A new radiotherapy technique for treating head and neck cancer
Shahrin Ahmed, medical specialist at Canadian Cancer Society, shared on X: "A new radiotherapy technique…
Jul 6, 2024, 12:24 | Career
Omnia Korani: I have been accepted into the JCO Trainee Reviewer Mentoring Program
Omnia Korani, Assistant Lecturer at the National Cancer Institute, shared a post on LinkedIn: "Exciting…
Jul 5, 2024, 13:47 | Insight
Andrea Apolo: Very proud of this Clinical Trial of Cabozantinib/Nivolumab published at JCO
Shilpa Gupta shared a post by Andrea Apolo, adding: "Huge congrats Andrea Apolo, leading this…
Jul 5, 2024, 06:54 | Blog
Paolo Tarantino: Nearly 1000 downloads in less than a week for our ATEMPT 5-year publication
Paolo Tarantino, posted on X: "Nearly 1000 downloads in less than a week for our…
Jul 4, 2024, 03:53 | Blog
Sarah Waliany: Reviewing the TRUST-1 trial investigating taletrectinib
Sarah Waliany, Thoracic Oncology Fellow at Mass General Cancer Center, shared the following post by…
Jul 3, 2024, 23:57 | Blog
Ajay Major: The newly-developed NLPHL prognostic score
Ajay Major, Assistant Professor at the University of Colorado School of Medicine and Founder and President…
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