March, 2025
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Cathy Eng: The Anti-CD47 Antibody Magrolimab with Cetuximab in Patients with Colorectal Cancer
Mar 28, 2025, 12:26

Cathy Eng: The Anti-CD47 Antibody Magrolimab with Cetuximab in Patients with Colorectal Cancer

Cathy Eng, Professor of Medicine, Hematology and Oncology, and is the Co-Director of GI Oncology, shared an article on LinkedIn:

“It has been my pleasure to work with Gilead Sciences on our multi-center phase I/II trial in heavily pre-treated metastatic colorectal cancer of anti- CD47 antibody (magrolimab) and EGFR therapy.

Median is equal 5 prior lines of therapy; 2 PRs; KRASwt and KRASmt CRC achieved SD (43.8% and 38.1%, respectively) and half of the patients with KRASwt CRC exhibited disease control rate disease (DCR, 50.0%). The median OS was 9.5 and 7.6 months in patients with KRASwt CRC and KRASmt CRC, respectively.

Absolute pleasure to work with my colleagues: Drs. Lakhani, Philip Agop Philip, Charles Schneider, Benny Johnson, Adel Kardosh, Mark P. Chao, Amita Patnaik, Fadi Shihadeh, Yeonju Lee, Kai Song, Denise Jin, Yanan Huo, Michael Howland, George A. Fisher, J. Randolph Hecht.

A Phase 1b/2 Study of the Anti-CD47 Antibody Magrolimab with Cetuximab in Patients with Colorectal Cancer and Other Solid Tumors.

Authors: Cathy Eng, et al.

Cathy Eng: The Anti-CD47 Antibody Magrolimab with Cetuximab in Patients with Colorectal Cancer