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Encorafenib, cetuximab, and chemotherapy in BRAF-mutant colorectal cancer
Feb 2, 2025, 04:22

Encorafenib, cetuximab, and chemotherapy in BRAF-mutant colorectal cancer

Arndt VogelManaging Senior Consultant and a Professor in the Department of Gastroenterology, Hepatology, and Endocrinology at Hannover Medical School, shared a paper by Scott Kopetz et al. on X:

“Encorafenib, cetuximab, and chemotherapy in BRAF-mutant colorectal cancer:

  • BREAKWATER Phase 3 trial
  • ORR 60% vs. 40.0%
  • DoR 13.9 vs. 11.1 months
  • OS NE vs. 14.6 months

New SOC for BRAF mutant CRC”

Encorafenib, cetuximab and chemotherapy in BRAF-mutant colorectal cancer: a randomized phase 3 trial

Authors: Scott Kopetz, Takayuki Yoshino, Eric Van Cutsem, Cathy Eng, Tae Won Kim, Harpreet Singh Wasan, Jayesh Desai, Fortunato Ciardiello, Rona Yaeger, Timothy S. Maughan, Elena Beyzarov, Xiaoxi Zhang, Graham Ferrier, Xiaosong Zhang & Josep Tabernero

Encorafenib, cetuximab, and chemotherapy in BRAF-mutant colorectal cancer