Ashish Manne: New AI Platform Nucleus Aims to Transform Clinical Decision-Making in Oncology
Ashish Manne/cancer.osu.edu

Ashish Manne: New AI Platform Nucleus Aims to Transform Clinical Decision-Making in Oncology

Ashish Manne, Associate Professor at Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute, shared on LinkedIn:

“Heading to Berlin, Germany, to proudly present Nucleus, our clinician-facing, AI-powered platform, at the ESMO AI and Digital Oncology Congress 2026.

A couple of years ago, as AI began gaining momentum in healthcare, we started thinking about how to translate its potential into meaningful improvements in everyday clinical practice. While AI holds tremendous promise, integrating it seamlessly into clinical workflows and demonstrating its practical value remain important challenges.

That led us to Nucleus, a ground-up, cancer-specific, institution-centered clinical intelligence platform designed to transform vast amounts of underutilized patient data into meaningful insights at the point of care.

Starting with pancreatic cancer, Nucleus helps clinicians identify comparable patients, understand their treatment journeys and outcomes, and visualize treatment-related toxicities – all within the routine clinical workflow. Our goal is to make the collective clinical experience of an institution accessible when caring for the next patient.

We recently completed our first round of clinical pilot testing, with wonderful support from Pannaga Malalur, Arjun Mittra, and Shafia Rahman and are now advancing toward a more comprehensive platform incorporating longitudinal treatment and toxicity intelligence.

I am proud to lead this initiative through a rewarding collaboration between The Ohio State University Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute and Microsoft, alongside a wonderful multidisciplinary team.

Looking forward to sharing our work and connecting with colleagues shaping the future of AI in oncology.”

About The ESMO AI and Digital Oncology Congress 2026

The ESMO AI & Digital Oncology Congress 2026 is an international congress organized by the European Society for Medical Oncology (ESMO), focusing on the application of artificial intelligence and digital technologies in oncology. The congress brings attention to the growing role of AI and digital innovation in the oncology field, providing a dedicated setting for exploring developments at the intersection of technology and cancer care. It highlights the importance of digital oncology as an evolving area within modern cancer research and clinical practice.

For more information, visit the official ESMO Congress page.

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Ashish Manne: New AI Platform Nucleus Aims to Transform Clinical Decision-Making in Oncology