Wafik S. El-Deiry, Director of Legorreta Cancer Center at Brown University and Chair of the WIN Consortium in Cancer Personalized Medicine, shared must-read papers on LinkedIn:
1.“During 2013–2022 incidence rates increased by 3% annually in adults aged 20–49 years…Rectal cancer incidence increased by 1% annually from 2018 to 2022 after decades of decline and now accounts for 32% of all CRC…
Urgent need for etiologic research to discover the cause of the rising trend…”
Title: Colorectal cancer statistics, 2026
Authors: Rebecca L. Siegel, Nikita Sandeep Wagle, Jessica Star, Tyler B. Kratzer, Robert A. Smith, Ahmedin Jemal
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2.“A logic-gated trispecific engager enhances macrophage killing of cancer cells in solid tumors.”
Title: A logic-gated trispecific engager enhances macrophage killing of cancer cells in solid tumors
Authors: Xiaotian Zhao, Weiqiang Jing, Ganyu Wang, Zhanyan Liu, Xinxin Xu, Maosen Han, Zhipeng Fu, Yulin Zhang, Zuolin Zheng, Jing Zhang, Longyu Bo, Xianghui Dong, Caiping Li, Yanhua Sun, Junfeng Zhang, Fabao Zhao, Nianzeng Xing, Kun Zhao, Xinyi Jiang
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3.“More research is needed to unravel causes, prevent or treat cancer in younger individuals.
Excerpt From
When I Got Aggressive Cancer At 29, I Couldn’t Believe What My Friends Began To Imply About My Diagnosis.”
Title: Meningeal blood vessel blockage enhances anti-glioblastoma immunity
Authors: Yixin Gao, Yushan Peng, Jiying Cheng, Xinyu Zhang, Jian Zhong, Chenfei Lu, Xudong Xing, Yanxing Lai, Huixin Sun, Xuechao Zeng, Zhiying Liu, Kejun He, Xinman Liu, Feizhe Xiao, Xiuxing Wang, Fan Bai, Nu Zhang
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4.“This is the review we published in January 2026.”
Title: COVID vaccination and post-infection cancer signals: Evaluating
patterns and potential biological mechanisms
Authors: Charlotte Kuperwasser and Wafik S. El-Deiry
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5.“There is no information in a Cell paper just published about the vaccination status of a clinical cohort that developed severe respiratory symptoms/pneumonia requiring hospitalization after SARS-CoV-2.
This is unexpected for a paper published in Cell that concludes in the abstract:
‘Together, these findings establish a causal link between prior viral pneu-
monia and lung tumorigenesis, underscoring the need for enhanced surveillance and targeted interventions to reduce post-COVID cancer risk.’
Or states in the discussion:
‘these findings carry significant implications for clinical care, including enhanced lung cancer surveillance in high-risk survivors and the indirect cancer-preventive benefits of vaccination, consistent with our experimental data showing that vaccination mitigated tumor promotion.’
I don’t understand how the authors, editors and reviewers at Cell would not have thought that was important to include, know about, comment on and discuss as part of the rigor of the study or even as a requirement for including the human clinical data in the manuscript.”
Title: Respiratory viral infections prime accelerated lung cancer growth
Authors: Wei Qian, Xiaoqin Wei, Andrew J. Barros, Xiangyu Ye, Haibo Zhang, Qing Yu, Samuel P. Young, Eric V. Yeatts, Yury Park, Chaofan Li, Sijie Hao, Gislane Almeida-Santos, Jinyi Tang, Harish Narasimhan, Nicole A. Kirk, Valeria Molinary, Ying Li, Li Li, Bimal N. Desai, Peter Chen, Kwon-Sik Park, Anny Xiaobo Zhou, Jeffrey M. Sturek, Wei Chen, In Su Cheon, Jie Sun
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6.Title: Immune evasive DNA donors and recombinases license kilobase-scale writing
Authors: Connor J. Tou, Keqiang Xie, Joana Ferreira da Silva, Pazhanichamy Kalailingam, Eliz Amar-Lewis, David Rufino-Ramos, William Sawyer, Madeline L. Eller, Jakob Starzyk, Ishita Majumdar, Jiao Wang, Danna Lee, Shaobo Yang, Ronald J. Meis, Gary A. Dahl, Jiahe Li, Richard Shan, Natalie Artzi, Patricia L. Musolino, Hao Wu, Benjamin P. Kleinstiver
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7.“The persistence of COVID-19 vaccine artifacts in bodily fluids and tissues: a systematic review
‘Until definitive studies comparing the rate of degradation of spike and nucleocapsid proteins in different tissues are demonstrated, absence of evidence of the nucleocapsid protein cannot be used definitively as evidence of absence of viral infection.’ ”
Title: The persistence of COVID-19 vaccine artifacts in bodily fluids and tissues: a systematic review
Authors: Edgar Selem, Mikolaj Raszek, Joseph Varon, Matthew Halma
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8.“Pleased to share study by Singh et al. from the laboratory of Professor Clark Chen in Neurosurgery at Brown University.”
Title: miR-181d coordinates homologous recombination and anti-tumor immune responses in glioblastoma
Authors: Gatikrushna Singh, Shilpi Singh, Iteeshree Mohapatra, Jay Hou, Andrew Ni, Debashis Barik, Haoyi Zheng, Stefan Kim, Mayur Sharma, Sean Lawler, Shobha Vasudevan, Efrosini Kokkoli, Sasmit Sarangi, Heinrich Elinzano, Eric T. Wong, Margot Martinez-Moreno, Ziya Gokaslan, Wafik El-Deiry, Clark C. Chen
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9.Title: The promises and challenges of neoantigen cancer vaccines
Authors: Patrick A. Ott
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10.Title: Homologous recombination deficiency and hemizygosity drive resistance in breast cancer
Authors: Anton Safonov, Minna Lee, David N. Brown, Luca Boscolo Bielo, Miika Mehine, Chaitanya Bandlamudi, Ben O’Leary, Hong Shao, Laia Vicente, Daniel Muldoon, Allen Zhu, Susana Ros, Antonio Marra, Pier Selenica, Ivan Bieche, Bradley Wubbenhorst, Emanuela Ferraro, Laura Courtois, Rania El Botty, Mehnaj Ahmed, Enrico Moiso, Julia Ah-Reum An, Mark T. A. Donoghue, Marie Will, Fresia Pareja, Emily Nizialek, Natalia Lukashchuk, Eleni Sofianopoulou, Yuan Liu, Xin Huang, Colombe Chappey, Anna D. Staniszewska, Dara Ross, Diana Mandelker, Marc Ladanyi, Nikolaus Schultz, Michael F. Berger, Maurizio Scaltriti, Jorge S. Reis-Filho, Bob T. Li, Kenneth Offit, Larry Norton, Ronglai Shen, Kara N. Maxwell, Fergus Couch, Susan M. Domchek, Elisabetta Marangoni, Sohrab Shah, Mark R. Albertella, Violeta Serra, Britta Weigelt, David B. Solit, Katherine L. Nathanson, Mark E. Robson, Nicholas C. Turner, Sarat Chandarlapaty, Pedram Razavi
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Other articles featuring Wafik S. El-Deiry on OncoDaily.
