Primary Endpoints in Randomized Controlled Trials for Older Adults with Cancer – SIOG
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Primary Endpoints in Randomized Controlled Trials for Older Adults with Cancer – SIOG

SIOG – International Society of Geriatric Oncology shared a post on LinkedIn:

“New in JGO

Primary endpoints in randomized controlled trials for older adults with cancer: A scoping review

What outcomes are clinical trials really measuring in older adults with cancer?

This review of 66 randomized controlled trials found that survival-based endpoints still dominate. Patient-relevant outcomes such as quality of life, functional status, and treatment tolerance were included far less often and showed wide variability in how they were defined and measured.

The findings highlight an opportunity to better align trial design with outcomes that matter to older patients.

SIOG members enjoy free online access to JGO.”

Title: Primary endpoints in randomized controlled trials for older adults with cancer: A scoping review

Authors: Tomonori Mizutani, Funato Sato, Kohei Uemura, Yukari Shimizu, Tsuguo Iwatani, Satoshi Kobayashi, Masataka Sawaki, Shimon Tashiro, Tetsuya Tsuji, Hiroshi Yamamoto, Asao Ogawa, Tetsuya Hamaguchi

Read the full article on Journal of Geriatric Oncology.

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