Paolo Ciracì
Paolo Ciracì/X

Paolo Ciracì: Final Results of the PARERE Study

Paolo Ciracì, Medical Oncology Resident at the University Hospital of Pisa, shared a post on X about a recent article he and his colleagues co-authored, published in Annals Oncology:

“Final results of the PARERE study in Annals Oncology

  • 428 mCRC pts screened via liquid biopsy for anti-EGFR re-tx
  • >⅓ RAS and/or BRAF mut in ctDNA
  •  No OS diff (pani→rego vs rego→pani)
  •  Higher ORR, DCR & PFS with pani, regardless of sequence”

Title: Re-treatment with panitumumab followed by regorafenib versus the reverse sequence in chemorefractory metastatic colorectal cancer patients with RAS and BRAF wild-type circulating tumor DNA: the PARERE study by GONO

Authors: P. Ciracì, M.M. Germani, F. Pietrantonio, P. Manca, S. Lonardi, A. Busico, F. Bergamo, V. Burgio, F. Mannavola, S. Di Donato, E. Fenocchio, F. Palermo, I. Capone, M.C. De Grandis, N. Pella, M. Scartozzi, L. Antonuzzo, A. Passardi, M. Claravezza, L. Salvatore, S. Tamberi, G. Randon, E. Conca, V. Conca, C. Antoniotti, R. Moretto, G. Masi, L. Boni, D. Rossini, C. Cremolini

Read the Full Article on Annals Oncology

Paolo Ciracì: Final Results of the PARERE Study

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