Narjust Florez, Co-Director of Young Lung Cancer Program at Dana-Farber Cancer Institute, shared a post on X:
“Our Alliance A221805 trial, published in JCO Oncology Advances, found that duloxetine did not prevent oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer.
Grateful to the patients and research teams who made this study possible.”
Title: Alliance A221805: Duloxetine to Prevent Oxaliplatin-Induced Chemotherapy-Induced Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase II Study
Authors: Ellen M. Lavoie Smith, Minji Lee, Mary R. Scott, Heshan Liu, Shauna Hillman, Tracy Rieken, Rachel Wills, Julian Diaz-Cobo, Selina Chow, Heidi D. Finnes, Kathryn Ruddy, Jeffrey Meyerhardt, Eileen O’Reilly, Tareq Al Baghdadi, Narjust Florez, Jordan Kharofa, Rang Govindarajan, Mohamedtaki Tejani, Ki Chung, David Zahrieh, Charles Loprinzi, Maryam Lustberg.

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