Murali Janakiram, Associate Professor at the Division of Hematological Malignancies, Myeloma, Cellular Immunotherapy and Immune Checkpoints at City of Hope, shared a post on X:
“KRD -24 cycles vs VRD – 6 cycles and then maintenance Len in each arm Phase 3
ENDURANCE- nearly all SR, duration of KRD 6 cycles
COBRA- SR+ HR
Main difference K continued till C24 , V stopped after 6 cycles
SR , HR- Hazard ratio-0.59, 0.52
No difference in OS as yet
Grade 3 cardiac events 6 vs 2%.”
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