Lung Cancer Europe shared a post on X:
“A liquid biopsy technique that could change how we detect and monitor lung cancer.
Most blood tests hunt for specific mutations but not all tumours shed enough DNA to find them. cfMeDIP-seq reads methylation patterns instead. A broader signal, detectable even when tumour DNA is low.
In lung cancer it outperformed CT risk scores for spotting malignant nodules. In ALK+ NSCLC it detected progression 3 months before imaging.”
Title: Circulating cell-free methylated DNA immunoprecipitation sequencing (cfMeDIP-seq) in oncology: from technological advances to clinical applications
Authors: Edoardo Francini, Sara Bleve, Giuseppe Nicolo Fanelli, Mara Serena Serafini, Filippo Pederzoli, Alessandra Ferri, Erika Minonne, Jacopo Venturini, Silvia Rodrigues, Hubert Pakula, Cristian Lolli, Massimo Cristofanilli, Pier Vitale Nuzzo
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