Laura Alder
Laura Alder, Sandip Patel and Tom Stinchcombe

Laura Alder: Which Should Come First for CNS Metastases – Radiation Therapy or CNS-Penetrant TKIs?

Laura Alder, Thoracic Medical Oncologist at Duke University School of Medicine, shared a post on LinkedIn:

“Proud to have contributed to one of my favorite article series, JTO “Controversies in Thoracic Oncology!”

We (myself, Sandip Patel, MD FASCO, and Tom Stinchcombe) argue why CNS-penetrant TKIs should be given first with close follow up imaging, while our very worthy opponents (Peter van Rossum and team) argue why RT remains a valid upfront choice. An important topic requiring careful MDC and patient-centric discussion.”

Title: Even With CNS-Penetrant TKIs, Radiation Therapy Should Be Used Before Systemic Therapy For CNS Metastases

Authors: Peter S.N. van Rossum, Sayed M.S. Hashemi, Joost J.C. Verhoeff, Patricia F. de Haan, Famke L. Schneiders, Suresh Senan,

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Laura Alder

Title: Given TKIs With High CNS Penetrance, Systemic Therapy Should Be Administered Before Radiation Therapy for CNS Metastases

Authors: Laura Alder, Sandip P. Patel, Thomas E. Stinchcombe,

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Laura Alder

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