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Jordan Gauthier: Modeling Hematologic Toxicity After CAR-T Using Time-Series Clustering
Jordan Gauthier/fredhutch.org

Jordan Gauthier: Modeling Hematologic Toxicity After CAR-T Using Time-Series Clustering

Jordan Gauthier, Associate Professor at Fred Hutch and at the University of Washington, shared a post on LinkedIn about a paper he co-authored with colleagues published in JCO Clinical Cancer Informatics:

“Very pleased to see our work, led by Dr. Emily Liang and Yein Jeon, finally published in JCO Clinical Cancer Informatics.

We explored some long-standing questions of mine:

  • Can we model hematologic toxicity after CAR-T cell therapy using time-series clustering methods?
  • Do the machines outperform the current, expert-based ICAHT grading criteria?

Online app.”

Title: Time-series clustering captures patterns of early immune effector cell-associated hematotoxicity that are predictable using tree-based models

Authors: Emily C. Liang, Yein Jeon, Yang Qiao, Xiancheng Wu, Jennifer J. Huang, Andrew J. Portuguese, Ryan Basom, Aiko Torkelson, Delaney Kirchmeier, Kristina Braathen, Andrew J. Cowan, Mazyar Shadman, Alexandre V. Hirayama, Brian G. Till, Erik L. Kimble, Qian Wu, Jordan Gauthier

You can read the Full Article in JCO Clinical Cancer Informatics.

Jordan Gauthier: Modeling Hematologic Toxicity After CAR-T Using Time-Series Clustering

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Aiko Torkelson Alexandre V. Hirayama Andrew J Cowan Andrew J. Portuguese Brian G. Till cancer Delaney Kirchmeier Emily C. Liang Emily Liang Erik L. Kimble Jennifer J. Huang Jordan Gauthier Kristina Braathen Mazyar Shadman OncoDaily Oncology Qian Wu Ryan Basom Xiancheng Wu Yang Qiao Yein Jeon