Invikafusp Alfa
Italiano Antoine and Zhen Su

Italiano Antoine: Phase 2 Invikafusp Alfa Data at ESMO 2025

Italiano Antoine, Professor of Medicine, Head of Early Phase Trials Unit at Institut Bergonié and Head of Precision Medicine at Gustave Roussy, shared a post on LinkedIn by Zhen Su, CEO at Marengo Therapeutics, adding:

“Honored to present the late-breaking Phase 2 data of Invikafusp alfa at ESMO 2025 on behalf of all the investigators, study teams, and most importantly, our patients.

These results illustrate the potential of harnessing fundamental T-cell biology to bring new options for patients with PD-1–resistant tumors across multiple solid cancers.

Grateful to Marengo Therapeutics for their trust and collaboration, and to all colleagues who made this possible.”

Quoting Zhen Su‘s post:

“We are thrilled to present initial Phase 2 Invikafusp alfa monotherapy clinical data from the STARt-001 trial, showcasing how unlocking fundamental T-cell biology can create new therapeutic options for patients whose tumors no longer respond to PD-1 checkpoint inhibitors.

We extend our heartfelt thanks to the outstanding clinical investigators, study sites, and—most importantly—the patients who placed their trust in this journey.”

Invikafusp Alfa

More from Zhen Su on OncoDaily.