Alina Comanescu, Vice Chair of the Board Digestive Cancer Europe, shared a post on LinkedIn:
“What happens when your body’s strongest defense system, the immune system, is tricked into protecting its biggest enemy: “Cancer”?
This year, the 2025 Nobel Prize in Physiology or Medicine recognizes a fundamental discovery that could transform the way we understand and treat cancer: regulatory T cells (Treg) and their role in peripheral immune tolerance. The laureates’ research showed that regulatory T cells (Treg) act as “gatekeepers” of the immune system, protecting the body from attacks by its own immune cells. However, in the context of cancer, these cells become a significant obstacle.
Why does this discovery matter? Because, in the context of cancer, many tumors “build protective walls” using exactly these T-reg cells. They help the tumor hide from the immune system, preventing the natural attack that could eliminate cancer cells.
This award celebrates not just a theory, but a knowledge base that paves the way for innovative therapies. We are on the verge of deactivating the tumor shield and unleashing the full power of our own immune system against the disease.”
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