Estela Rodriguez: Melanoma Opens the Door for Personalized mRNA Cancer Therapy
Estela Rodriguez/X

Estela Rodriguez: Melanoma Opens the Door for Personalized mRNA Cancer Therapy

Estela Rodriguez, Associate Director of Community Outreach for Thoracic Oncology and Co-Lead of the Thoracic Site Disease Group at Sylvester Comprehensive Cancer Center, shared on X:

Melanoma research lead the way in the approval of checkpoint inhibitors. Excited to see this Merck and Moderna press release about the positive pivotal Phase 3 INTerpath-001 trial in resected stage IIB–IV melanoma, RFS were significantly improved vs pembrolizumab alone. ~1,100 patients.

This is precision immuno-oncology at the individual neoantigen patient level.

Now the big question:

Can we reproduce this across lung, bladder, and other solid tumors? “

Quoting Merck:

“In collaboration with Moderna, we’re excited to share the first positive Phase 3 topline results for our investigational individualized neoantigen therapy (INT) in combination with our company’s immunotherapy in the adjuvant setting for certain patients with completely resected stage IIB-IV”

You can also read:Melanoma Research Foundation Highlights New CURE OM Report

Estela Rodriguez: Melanoma Opens the Door for Personalized mRNA Cancer Therapy