Davood Khoda-Amorzideh, Clinical Cardiologist at Farjam Heart Clinic, shared a post on LinkedIn:
“Abemaciclib carries a high risk of VTE and shows a hypothesis-generating signal for supraventricular arrhythmias. Ribociclib increases the risk of QTc prolongation.
Palbociclib shows no consistent cardiovascular safety concerns to date.”
Title: Risk of QTc prolongation, and major cardiovascular adverse events associated with CDK4/6 inhibitors in hormone receptor-positive HER2-negative breast cancer – A systematic review and meta-analysis
Authors: Yee-Yin Hoo, Wei-Wei Sia, Sharminii Jaya-Prakason, Bogda Koczwara, Yek-Ching Kong, Joe-Elie Saleme, Agnès Dechartres, Nirmala Bhoo-Pathy
Read the Full Article.
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