Charles Gaulin, Hematologic Oncologist and Assistant Professor of Medicine at Dartmouth Hitchcock Medical Center and Clinics, shared a post on LinkedIn:
“At Dartmouth’s Rural Health Symposium, William P., an MS2 on our team, presented a retrospective analysis looking at the intersection of psychiatric burden and immune effector cell (IEC) toxicities.
Interestingly, the data showed an inverse association between pre-existing mental health disorders and the incidence of CRS in patients receiving CAR-T bispecific therapies – a signal that persisted independently of area-level structural deprivation in our rural-serving cohort.
This hypothesis-generating data stimulated interesting discussion regarding the neuro-immune axis and the potential modulatory effects of psychotropic medications during his session.
Authors: William Patterson, Chad Markey, Kelsey Kuwahara, Sivan Rotenberg, Brian Rosen, Parth Shah, Frederick Lansigan, Ivy Riano, Charles Gaulin”
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