Aakash Desai HER2-Mutant NSCLC: Navigating the TKI vs ADC Debate
Aakash Desai/LinkedIn

Aakash Desai HER2-Mutant NSCLC: Navigating the TKI vs ADC Debate

Aakash Desai, Assistant Professor and Associate Director of Phase 1 and Precision Oncology Program at the UAB O’Neal Comprehensive Cancer Center, shared a post on LinkedIn:

“HER2-Mutant NSCLC: The TKI vs ADC Debate Heats Up.

With three FDA-approved options now available for HER2-mutant non-small cell lung cancer, the treatment landscape is evolving rapidly. Here’s how they compare.

Key takeaway: Zongertinib’s clean safety profile (17% Grade 3+ AE rate) and high first-line ORR make it a compelling choice – but T-DXd still has mature OS data in 2L and where does TKI post TKI fit?

The sequencing question remains?”

Aakash Desai

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