Sep 7, 2023, 19:44
Iyad Sultan: A Mixed Bag in Pediatric B-ALL Treatment!
Quoting Iyad Sultan, Chairman and Professor, Department of Pediatrics, King Hussein Cancer Center and a Board Member of OncoDaily, on X/Twitter:
” A Mixed Bag in Pediatric B-ALL Treatment!
AALL1331 Phase III trial finds blinatumomab greatly improves DFS & OS in 2/3 of Low-Risk B-ALL kids with combined BM ± EM relapse, making this a new standard of care.
4-yr DFS: 72.7% vs 53.7% (chemo)
4-yr OS: 97.1% vs 84.8% (chemo)
However, no significant difference was observed for patients with isolated EM relapse. More research is needed.”
Source: Iyad Sultan/Twitter
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