Pratiti Bandopadhayay: The Clinical Significance of FGFR-Alterations Across Pediatric Gliomas
Pratiti Bandopadhayay, Associate Professor of Pediatrics at Harvard Medical School, shared a post on LinkedIn about a recent article by April A. Apfelbaum et al. published in Nature Communications:
“Very excited to share our paper reporting the clinical significance of FGFR-alterations across pediatric gliomas.
We still have a lot of work to do until we get to our goal of having targeted inhibitors for children diagnosed with these gliomas, but are hoping that this work increases awareness around the need for drug development and access to drugs for children.
Congratulations to first authors April Apfelbaum and Eric Morin and to everyone across BandoLab and Ligon Lab and our collaborators who spearheaded this project and contributed. And a massive thank you to all of the foundations and patients and their families without whom this would have been impossible.”
Title: A diverse landscape of FGFR alterations andco-mutations suggests potential therapeuticstrategies in pediatric low-grade gliomas
Authors: April A. Apfelbaum, Eric Morin, Dominik Sturm, Georges Ayoub, Jeromy DiGiacomo, Sher Bahadur, Bhavyaa Chandarana, Phoebe C. Power, Margaret M. Cusick, Dana Novikov, Prem Prabhakar, Robert E. Jones, Jayne Vogelzang, Connor C. Bossi, Seth Malinowski, Lewis M. Woodward, Tania A. Jones, John Jeang, Sarah W. Lamson, Jared Collins, Kelly Y. Cai, Jacquelyn S. Jones, Sehee Oh, Hyesung Jeon, Jinhua Wang, Amy Cameron, Patrick Rechter, Angela De Leon, Karthikeyan Murugesan, Meagan Montesion, Lee A. Albacker, Shakti H. Ramkissoon, Cornelis M. van Tilburg, Emily C. Hardin, Philipp Sievers, Felix Sahm, Kee Kiat Yeo, Tom Rosenberg, Susan N. Chi, Karen D. Wright, Steven Hébert, Sydney Peck, Alberto Picca, Valérie Larouche, Samuele Renzi, Sara J. Buhrlage, Tejus A. Bale, Amy A. Smith, Mehdi Touat, Nada Jabado, Eric S. Fischer, Michael J. Eck, Lissa Baird, Olaf Witt, Claudia L. Kleinman, Quang-De Nguyen, Denise Sheer, Sanda Alexandrescu, David T. W. Jones, Keith L. Ligon, Pratiti Bandopadhayay
Read the Full Article on Nature Communications
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