Nicola Gökbuget: GMALL Initial-1 Trial has been published in the Journal of Clinical Oncology
Nicola Gökbuget, Head of Clinical Trial Center at Goethe University Hospital, shared a post on LinkedIn:
“The German Multicenter Study Group for Adult Acute Lymphoblastic Leukemia (GMALL) is happy to announce that the GMALL Initial-1 Trial has been published in the Journal of Clinical Oncology.
In this trial it was demonstrated that an innovative induction therapy with the CD22-directed conjugated antibody Inotuzumab Ozogamicin induces a high complete remission rate with limited toxicity in older patients with newly diagnosed Ph-negative B-Precursor ALL. Subsequent age-adapted standard chemotherapy was tolerated well leading to a favorable overall survival of 73% at 3 years. These results represent a considerable progress for the management of older patients with ALL and will be considered for planned subsequent GMALL treatment optimization trials.”
Source: Nicola Gökbuget/LinkedIn
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