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Elisabetta Munzone: CTCs enumeration as an early treatment monitoring tool in metastatic breast cancer
Mar 22, 2025, 06:46

Elisabetta Munzone: CTCs enumeration as an early treatment monitoring tool in metastatic breast cancer

Elisabetta Munzone, Medical oncologist and Breast Cancer specialist at the European Institute of Oncology shared on X about recent paper by Wolfgang Janni et al., titled “Clinical validity of repeated circulating tumor cell enumeration as an early treatment monitoring tool for metastatic breast cancer in the PREDICT global pooled analysis” published on AACR Journals.

Authors: Wolfgang Janni et al.

“PREDICT Global Analysis confirms the clinical validity of repeated CTCs enumeration as an early treatment monitoring tool in metastatic breast cancer.

Among 4,436 patients, follow-up CTC status was strongly prognostic for OS, independent of tumor subtype and treatment.

CTC responders (positive to negative) had significantly better OS than non-responders (positive to positive) (HR 0.48, 95% CI 0.44–0.53).”

Elisabetta Munzone: CTCs enumeration as an early treatment monitoring tool in metastatic breast cancer