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Niklas Klümper: Dissection of Progressive Disease Patterns for a Modified Classification for Immunotherapy

Niklas Klümper/X

Dec 27, 2024, 14:10

Niklas Klümper: Dissection of Progressive Disease Patterns for a Modified Classification for Immunotherapy

Niklas Klümper, Senior Urology Consultant at the University Medical Center Bonn, shared a recent article on X:

“Happy to share our manuscript titled Dissection of Progressive Disease Patterns for a Modified Classification for Immunotherapy published today in JAMA Oncology and JAMA.

We introduce a new and straightforward PD classification (low, intermediate, high risk) that enhances post progression survival predictions in 1377 immunotherapy-treated patients across solid tumors.

New PD classification with 3 risk levels:

– low risk: progression of only existing lesions.

– intermediate risk: new lesions without progression of existing lesions.

– high risk: progression of existing lesions plus new lesions.”

Title: Dissection of Progressive Disease Patterns for a Modified Classification for Immunotherapy

Authors: Jonas Saal, Markus Eckstein, Manuel Ritter, Peter Brossart, Julian Luetkens, Jörg Ellinger, Viktor Grünwald, Michael Hölzel and Niklas Klümper

Niklas Klümper: Dissection of Progressive Disease Patterns for a Modified Classification for Immunotherapy

Niklas Klümper, MD, is a senior urology consultant specializing in genitourinary (GU) oncology and an advanced clinician-scientist at the University Medical Center Bonn (UKB), supported by the BMBF-funded ACCENT program. He leads a translational uro-oncology research group that bridges the Department of Urology and the Institute of Experimental Oncology. His research focuses on improving treatment response predictions for targeted therapies, developing personalized treatment strategies, and conducting clinical trials to enhance outcomes for patients with uro-oncological diseases.

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