Five articles suggested by Yüksel Ürün
Yüksel Ürün is a Medical Oncology professor at Ankara University School of Medicine in Turkey. His research focuses on genitourinary cancers, covering epidemiology, diagnosis, biomarkers, meta-analysis, and treatment outcomes. His dedication to patient care and research inspires positive change in the medical field.
He suggested following few must-read papers on X:
1.”HIPEC Extends Survival in Recurrent Ovarian Cancer.
The CHIPOR trial shows adding HIPEC to cytoreductive surgery improves survival:
- 54.3 months OS with HIPEC vs. 45.8 months without.
- Higher grade ≥3 toxicities.”
Authors: Prof Jean-Marc Classe, et al.
2.”Adolescents and young adults (AYA) Cancer: Global Trends & Challenges.
In 2022, 1.3M adolescents & young adults (15–39) faced cancer, with disparities by region:
- 57% fatality in low-income settings vs. 12% in high-income settings.
- A projected 102% increase in low HDI countries by 2050.
Prioritize global equity in cancer care.”
Authors: Taylor Hughes, et al.
3.”RADICALS-HD: Adding ADT to postop RT in prostate cancer shows no MFS improvement. Long-term outcomes remain favorable, even without ADT. High-risk cases need focus!
A total of 492 participants due for radiotherapy (RT) after previous prostate cancer surgery were allocated to RT alone, RT with 6 mo of hormone therapy, or RT with 24 mo of hormone therapy. No meaningful differences were seen in long-term outcomes between the three groups.”
Authors: Chris C Parker, et al.
4.”Mechanisms of resistance to PARP inhibitors in advanced prostate cancer with BRCA2/PALB2 alterations: Reversion mutations emerge within 16 weeks. These associate with disease progression and survival.”
Elucidating acquired PARP inhibitor resistance in advanced prostate cancer.
Authors: George Seed, et al.
5.”New research reveals an ‘obesogenic memory’ in adipose tissue driven by epigenetic changes, fueling rebound weight gain after dieting.
A key to ending the yo-yo effect? “
Adipose tissue retains an epigenetic memory of obesity after weight loss.
Authors: Laura C. Hinte, et al.
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