Photo from Raffaele Colombo/X
Nov 4, 2023, 00:58
Raffaele Colombo: Here the breakdown of the Monomethyl auristatin E Antibody Drug Conjugates
Raffaele Colombo, Principal Scientist at Zymeworks, shared on X/Twitter:
106 auristatin Antibody Drug Conjugates (ADCs) have reached clinic development, of which two-thirds (= 71 ADC) with Monomethyl auristatin E (MMAE) as payload! Here the breakdown of the MMAE ADCs:
- 4 approved by FDA
- 1 approved by the National Medical Products Administration in China
- 41 in clinical development
- 25 discontinued
The MMAE history:
Source: Raffaele Colombo/Twitter
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