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Talha Badar: Prognostic impact of ‘multi-hit’ versus ‘single-hit’ TP53 alteration in patients with AML
Nov 7, 2024, 15:22

Talha Badar: Prognostic impact of ‘multi-hit’ versus ‘single-hit’ TP53 alteration in patients with AML

Talha Badar posted on X about recent paper by him as first author, titled “Prognostic impact of ‘multi-hit’ versus ‘single-hit’ TP53 alteration in patients with acute myeloid leukemia: results from the Consortium on Myeloid Malignancies and Neoplastic Diseases” published on Haematalogica.

Authors: Talha Badar, Ahmad Nanaa, Ehab Atallah, Rory M. Shallis, Emily C. Craver, Zhuo Li, Aaron D. Goldberg, Antoine N. Saliba, Anand Patel, Jan P. Bewersdorf, Adam Duvall, Madelyn Burkart, Danielle Bradshaw, Yasmin Abaza, Maximilian Stahl, Neil Palmisiano, Guru Subramanian Guru Murthy, Amer M. Zeidan, Vamsi Kota, Mrinal M. Patnaik, Mark R. Litzow

Talha Badar: Prognostic impact of ‘multi-hit’ versus ‘single-hit’ TP53 alteration in patients with AML

“Finally available online, free access: Prognostic impact of ‘multi-hit’ versus ‘single-hit’ TP53 alteration in patients with acute myeloid leukemia: results from the Consortium on Myeloid Malignancies and Neoplastic Diseases (COMMAND)

We analyzed:

1. Impact of allelic burden on outcome including transplant.
2. Outcome with or without complex CG
3. Impact of concurrent somatic mutation on outcome.”

Dr. Talha Badar, MD, is a specialist in Hematology Oncology based in Mayo Clinic, Jacksonville, Florida. His primary areas of expertise include Leukemia, particularly Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Acute Lymphoblastic Leukemia (ALL), and Bone Marrow Transplantation. Over his career, he has actively contributed to clinical research and clinical trials.