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Patients with ERBB2 exon 20 insertion mutations showed particularly encouraging outcomes – Elie G. Dib
ihacares.com
Jun 15, 2023, 15:56

Patients with ERBB2 exon 20 insertion mutations showed particularly encouraging outcomes – Elie G. Dib

Excited to share that our study, published in JCO Precision Oncology, sheds light on the antitumor activity of pertuzumab plus trastuzumab (P + T) in advanced lung cancer patients with ERBB2 mutation or amplification. The Targeted Agent and Profiling Utilization Registry (TAPUR) Study demonstrated promising results, with a disease control rate of 37% and an objective response rate of 11%. Notably, patients with ERBB2 exon 20 insertion mutations showed particularly encouraging outcomes. These findings offer hope for heavily pretreated non-small-cell lung cancer patients. Grateful to the team and the American Society of Clinical Oncology for their support.

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Elie G. Dib ERBB2 JCO Precision Oncology pertuzumab TAPUR trastuzumab
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